Route Map
Day-by-Day Itinerary
Day 1
Saint Paul, Minnesota
United States
Explore the Minnesota History Center's impressive collections and stroll through vibrant neighborhoods along the scenic Mississippi River.
Arrive
2026-06-12 00:00:00
Day 2
🌊 At Sea
Day 3
La Crosse, Wisconsin
United States
Cruise passengers can ride scenic riverboats through the majestic bluffs of the Upper Mississippi River Valley.
Arrive
2026-06-14 00:00:00
Day 4
🌊 At Sea
Day 5
Dubuque, Iowa
United States
Ride the historic riverboat casino and watch the Mississippi River roll by from scenic bluffs that rise 188 feet above the water.
Arrive
2026-06-16 00:00:00
Day 6
Davenport, Iowa
United States
Witness the mighty Mississippi River from the Figge Art Museum's stunning riverfront galleries in Iowa's cultural heartland.
Arrive
2026-06-17 00:00:00
Day 7
Hannibal, Missouri
United States
Explore the childhood home of Mark Twain and retrace the adventures of Tom Sawyer along the mighty Mississippi River.
Arrive
2026-06-18 00:00:00
Day 8
🌊 At Sea
About This Cruise
Set off on an exhilarating journey on the Upper Mississippi River, where every moment resonates with the essence of hometown Americana and the breathtaking beauty that has captivated the imaginations of our nation's most revered writers, artists, and musicians. Feel the heartbeat of the great American spirit as you follow in the footsteps of literary legend Mark Twain, who found inspiration amidst the grandeur of the river and its cascading bluffs, immortalizing them in his iconic tales. Step into the pages of history as you travel to Hannibal, the very town that shaped Twain's storytelling, where the colorful characters of Huck Finn, Tom Sawyer, and Becky Thatcher spring to life. From the comfort of your own private balcony, take in the unspoiled landscapes, adorned with playful wildlife. Navigate through a labyrinth of enchanting islands and get up close to the ingenious engineering of dams and locks.As the river twists and turns, all your meals will reflect the landscape you pass. Every dish is thoughtfully curated, infused with the essence of local ingredients, ensuring each bite is a celebration of the rich culture that lines the shores of the upper Mississippi. Join our river cruise from St. Louis to St. Paul and let the energy of this remarkable journey ignite your spirit and leave you with memories to cherish for a lifetime.
From $4,472 per person
7 nights on
American Melody
with
American Cruise Lines
Visit American
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