Upper Mississippi (St. Paul to St. Louis)

📅 Friday, June 12, 2026 🏁 Saturday, June 20, 2026 🌙 7 Nights Saint Paul, Minnesota 🚢 American Melody

Route Map

Day-by-Day Itinerary

Day 1
Saint Paul, Minnesota United States Explore the Minnesota History Center's impressive collections and stroll through vibrant neighborhoods along the scenic Mississippi River.
Arrive 2026-06-12 00:00:00
Day 2
🌊 At Sea
Day 3
La Crosse, Wisconsin United States Cruise passengers can ride scenic riverboats through the majestic bluffs of the Upper Mississippi River Valley.
Arrive 2026-06-14 00:00:00
Day 4
🌊 At Sea
Day 5
Dubuque, Iowa United States Ride the historic riverboat casino and watch the Mississippi River roll by from scenic bluffs that rise 188 feet above the water.
Arrive 2026-06-16 00:00:00
Day 6
Davenport, Iowa United States Witness the mighty Mississippi River from the Figge Art Museum's stunning riverfront galleries in Iowa's cultural heartland.
Arrive 2026-06-17 00:00:00
Day 7
Hannibal, Missouri United States Explore the childhood home of Mark Twain and retrace the adventures of Tom Sawyer along the mighty Mississippi River.
Arrive 2026-06-18 00:00:00
Day 8
🌊 At Sea

About This Cruise

Set off on an exhilarating journey on the Upper Mississippi River, where every moment resonates with the essence of hometown Americana and the breathtaking beauty that has captivated the imaginations of our nation's most revered writers, artists, and musicians. Feel the heartbeat of the great American spirit as you follow in the footsteps of literary legend Mark Twain, who found inspiration amidst the grandeur of the river and its cascading bluffs, immortalizing them in his iconic tales. Step into the pages of history as you travel to Hannibal, the very town that shaped Twain's storytelling, where the colorful characters of Huck Finn, Tom Sawyer, and Becky Thatcher spring to life. From the comfort of your own private balcony, take in the unspoiled landscapes, adorned with playful wildlife. Navigate through a labyrinth of enchanting islands and get up close to the ingenious engineering of dams and locks. As the river twists and turns, all your meals will reflect the landscape you pass. Every dish is thoughtfully curated, infused with the essence of local ingredients, ensuring each bite is a celebration of the rich culture that lines the shores of the upper Mississippi. Join our river cruise from St. Louis to St. Paul and let the energy of this remarkable journey ignite your spirit and leave you with memories to cherish for a lifetime.
Mississippi River
From $4,472 per person 7 nights on American Melody with American Cruise Lines
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