Route Map
Day-by-Day Itinerary
Day 1
Pittsburgh, Pennsylvania
United States
Explore three iconic steel bridges and world-class museums along the scenic confluence of three rivers in America's revitalized Steel City.
Arrive
2026-07-03 00:00:00
Day 2
🌊 At Sea
Day 3
Wheeling, West Virginia
United States
Explore the magnificent Wheeling Suspension Bridge, an engineering marvel spanning the Ohio River with breathtaking views and rich Civil War history.
Arrive
2026-07-05 00:00:00
Day 4
Marietta, Ohio
United States
Explore the historic Ohio River confluence where America's frontier began at the Campus Martius Museum and charming riverfront district.
Arrive
2026-07-06 00:00:00
Day 5
🌊 At Sea
Day 6
Cincinnati, Ohio
United States
Explore America's most intact Victorian riverfront and discover world-class museums in this historic Ohio River gateway city.
Arrive
2026-07-08 00:00:00
Day 7
Madison, Indiana
United States
Explore perfectly preserved Victorian architecture and stroll charming riverfront streets in this gem of a 19th-century river town.
Arrive
2026-07-09 00:00:00
Day 8
Louisville, Kentucky
United States
Cruise into the birthplace of bourbon and explore the legendary distilleries that shaped American whiskey history.
Arrive
2026-07-10 00:00:00
About This Cruise
This brand new 9-day voyage is a celebration of America’s heartland, inviting you to experience the remarkable history and natural beauty that graces the banks of the iconic Ohio River.Revel in the excitement of the Kentucky Derby at Churchill Downs and explore the rich bourbon heritage of Louisville with a visit to one of its famed distilleries. Experience Madison, boasting one of the largest National Historic Landmark Districts in the country. Journey to the vibrant riverfront city of Cincinnati boasting world-class museums and the first professional baseball team in the U.S.Spend a day cruising the Ohio River, where gentle currents and diverse landscapes make for a relaxing and picturesque adventure. Travel to Marietta, the first permanent settlement in the Northwest Territory, and a testament to America's early frontier days. Conclude your journey in “Steel City” Pittsburgh where you can admire its stunning skyline punctuated by iconic bridges.
From $3,790 per person
7 nights on
American Melody
with
American Cruise Lines
Visit American
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