Ohio River (Pittsburgh to Louisville)

📅 Friday, July 3, 2026 🏁 Saturday, July 11, 2026 🌙 7 Nights Pittsburgh, Pennsylvania 🚢 American Melody
Suite $7,020 per person
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Route Map

Day-by-Day Itinerary

Day 1
Pittsburgh, Pennsylvania United States Explore three iconic steel bridges and world-class museums along the scenic confluence of three rivers in America's revitalized Steel City.
Arrive 2026-07-03 00:00:00
Day 2
🌊 At Sea
Day 3
Wheeling, West Virginia United States Explore the magnificent Wheeling Suspension Bridge, an engineering marvel spanning the Ohio River with breathtaking views and rich Civil War history.
Arrive 2026-07-05 00:00:00
Day 4
Marietta, Ohio United States Explore the historic Ohio River confluence where America's frontier began at the Campus Martius Museum and charming riverfront district.
Arrive 2026-07-06 00:00:00
Day 5
🌊 At Sea
Day 6
Cincinnati, Ohio United States Explore America's most intact Victorian riverfront and discover world-class museums in this historic Ohio River gateway city.
Arrive 2026-07-08 00:00:00
Day 7
Madison, Indiana United States Explore perfectly preserved Victorian architecture and stroll charming riverfront streets in this gem of a 19th-century river town.
Arrive 2026-07-09 00:00:00
Day 8
Louisville, Kentucky United States Cruise into the birthplace of bourbon and explore the legendary distilleries that shaped American whiskey history.
Arrive 2026-07-10 00:00:00

About This Cruise

This brand new 9-day voyage is a celebration of America’s heartland, inviting you to experience the remarkable history and natural beauty that graces the banks of the iconic Ohio River. Revel in the excitement of the Kentucky Derby at Churchill Downs and explore the rich bourbon heritage of Louisville with a visit to one of its famed distilleries. Experience Madison, boasting one of the largest National Historic Landmark Districts in the country. Journey to the vibrant riverfront city of Cincinnati boasting world-class museums and the first professional baseball team in the U.S. Spend a day cruising the Ohio River, where gentle currents and diverse landscapes make for a relaxing and picturesque adventure. Travel to Marietta, the first permanent settlement in the Northwest Territory, and a testament to America's early frontier days. Conclude your journey in “Steel City” Pittsburgh where you can admire its stunning skyline punctuated by iconic bridges.
From $3,790 per person 7 nights on American Melody with American Cruise Lines
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