Ohio River (Pittsburgh to Louisville)
Route Map
Day-by-Day Itinerary
Day 1
Pittsburgh, Pennsylvania
United States
Explore three iconic steel bridges and world-class museums along the scenic confluence of three rivers in America's revitalized Steel City.
Arrive
2026-07-04 00:00:00
Day 2
Pittsburgh, Pennsylvania
United States
Explore three iconic steel bridges and world-class museums along the scenic confluence of three rivers in America's revitalized Steel City.
Arrive
2026-07-05 00:00:00
Day 3
Moundsville, West Virginia
United States
Explore the haunted West Virginia State Penitentiary, a Gothic fortress where visitors can experience spine-tingling ghost tours through its infamous cellblocks.
Arrive
2026-07-06 00:00:00
Day 4
Marietta, Ohio
United States
Explore the historic Ohio River confluence where America's frontier began at the Campus Martius Museum and charming riverfront district.
Arrive
2026-07-07 00:00:00
Day 5
🌊 At Sea
Day 6
Maysville, Kentucky
United States
Trace American frontier history and bourbon heritage along the scenic Ohio River at this charming 19th-century riverport town.
Arrive
2026-07-09 00:00:00
Day 7
Cincinnati, Ohio
United States
Explore America's most intact Victorian riverfront and discover world-class museums in this historic Ohio River gateway city.
Arrive
2026-07-10 00:00:00
Day 8
Louisville, Kentucky
United States
Cruise into the birthplace of bourbon and explore the legendary distilleries that shaped American whiskey history.
Arrive
2026-07-11 00:00:00
Day 9
Louisville, Kentucky
United States
Cruise into the birthplace of bourbon and explore the legendary distilleries that shaped American whiskey history.
Arrive
2026-07-12 00:00:00
About This Cruise
From $3,790 per person
8 nights on
American Melody
with
American Cruise Lines
Visit American
↗
