Complete Mississippi

📅 Saturday, June 13, 2026 🏁 Sunday, July 5, 2026 🌙 22 Nights New Orleans, Louisiana 🚢 American Serenade
Suite $21,361 per person
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Route Map

Day-by-Day Itinerary

Day 1
New Orleans, Louisiana United States Jazz-filled streets and Creole cuisine in the French Quarter transport you to a world where history, music, and flavor dance together.
Arrive 2026-06-13 00:00:00
Day 2
🌊 At Sea
Day 3
Oak Alley, Louisiana United States Stroll beneath a majestic canopy of 300-year-old oak trees lining the grand plantation mansion.
Arrive 2026-06-15 00:00:00
Day 4
Houmas House, Louisiana United States Explore an opulent antebellum mansion surrounded by sprawling gardens and glimpse Louisiana's grand plantation heritage.
Arrive 2026-06-16 00:00:00
Day 5
Baton Rouge, Louisiana United States Explore the magnificent Louisiana State Capitol, a 34-story Art Deco masterpiece offering panoramic river views and fascinating political history.
Arrive 2026-06-17 00:00:00
Day 6
Saint Francisville, Louisiana United States Explore stunning antebellum mansions nestled among Spanish moss-draped oaks along the serene Mississippi River bluffs.
Arrive 2026-06-18 00:00:00
Day 7
Natchez, Mississippi United States Tour antebellum mansions perched on bluffs overlooking the Mississippi River where Southern history comes vividly alive.
Arrive 2026-06-19 00:00:00
Day 8
Vicksburg, Mississippi United States Explore Civil War battlefields and monuments at this historic riverside bluff that shaped American history.
Arrive 2026-06-20 00:00:00
Day 9
Greenville, Mississippi United States Explore the haunting history of the Mississippi Delta where blues music was born and civil rights struggles shaped America's soul.
Arrive 2026-06-21 00:00:00
Day 10
Tunica, Mississippi United States Roll the dice at world-class casinos nestled along the Mississippi River in this thrilling gaming destination.
Arrive 2026-06-22 00:00:00
Day 11
Memphis, Tennessee United States Dive into musical history at Graceland, Elvis Presley's legendary mansion and the second-most visited private home in America.
Arrive 2026-06-23 00:00:00
Day 12
Cape Girardeau, Missouri United States Discover the mighty Mississippi River's history at the Gateway Arch-inspired riverfront while exploring charming downtown shops and authentic regional cuisine.
Arrive 2026-06-24 00:00:00
Day 13
🌊 At Sea
Day 14
Saint Louis, Missouri United States Gaze up at the iconic Gateway Arch while strolling the revitalized riverfront that seamlessly blends St. Louis's rich history with modern urban charm.
Arrive 2026-06-26 00:00:00
Day 15
🌊 At Sea
Day 16
Hannibal, Missouri United States Explore the childhood home of Mark Twain and retrace the adventures of Tom Sawyer along the mighty Mississippi River.
Arrive 2026-06-28 00:00:00
Day 17
🌊 At Sea
Day 18
Muscatine, Iowa United States Discover the Mississippi River's pearl heritage and stroll charming riverfront trails lined with historic architecture and local art galleries.
Arrive 2026-06-30 00:00:00
Day 19
Dubuque, Iowa United States Ride the historic riverboat casino and watch the Mississippi River roll by from scenic bluffs that rise 188 feet above the water.
Arrive 2026-07-01 00:00:00
Day 20
🌊 At Sea
Day 21
Winona, Minnesota United States Explore the dramatic bluffs and rich riverboat heritage along the scenic Mississippi River in this charming historic town.
Arrive 2026-07-03 00:00:00
Day 22
Red Wing, Minnesota United States Explore the Mississippi River's scenic bluffs and historic riverfront charm at this picturesque Minnesota gem nestled where water and nature converge.
Arrive 2026-07-04 00:00:00
Day 23
Saint Paul, Minnesota United States Explore the Minnesota History Center's impressive collections and stroll through vibrant neighborhoods along the scenic Mississippi River.
Arrive 2026-07-05 00:00:00

About This Cruise

The echoes of riverboat travelers from a bygone era resound as we travel the full length of the Mighty Mississippi. As ten states glide past your vantage point on the sun deck, admire what has been the subject of numerous works of art and the backdrop for countless American novels. From the vibrant cultural center of the “Big Easy” to the dramatic landscapes of the Upper Mississippi, experience life as it once was on the western frontier. Our expert guides will take you to the grand southern plantations, stately antebellum houses, and Civil War battlefields of the Lower Mississippi. Taste the finest Cajun and Creole and enjoy mouth-watering Memphis BBQ as you travel to the birthplace of Jazz, Blues, and Rock–n-Roll. Cruising up the river, Hometown Americana takes center stage. Relive the adventures of Mark Twain’s time on a trolley ride through Hannibal, his boyhood hometown. Experience the legacy of John Deere in Davenport and the Victorian-era elegance of Dubuque. As we continue north, pasture gives way to forest and the wild life of Minnesota and Wisconsin comes into view. Just as it was in Mark Twain’s day, every cruise on the Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary. The river has a mind of its own and our sailing schedules must adapt to it. This is part of the adventure and American Cruise Lines will always work to provide a seamless travel experience.
Mississippi River
From $11,817 per person 22 nights on American Serenade with American Cruise Lines
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