Point-to-Point

New Orleans, Louisiana to South Saint Paul, Minnesota Cruises

6 Cruises 1 Cruise Lines

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Cruise Line Cruises Ships From Duration Next Sailing
Viking River Cruises 6 1 $10,495 14-21 nights Jul 18, 2026

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Ports on This Route

Burlington, Iowa

Explore the stunning Mississippi River bluffs and discover riverside charm at this historic Iowa port town.

Dubuque, Iowa

Ride the historic riverboat casino and watch the Mississippi River roll by from scenic bluffs that rise 188 feet above the water.

Greenville, Mississippi

Explore the haunting history of the Mississippi Delta where blues music was born and civil rights struggles shaped America's soul.

Hannibal, Missouri

Explore the childhood home of Mark Twain and retrace the adventures of Tom Sawyer along the mighty Mississippi River.

La Crosse, Wisconsin

Cruise passengers can ride scenic riverboats through the majestic bluffs of the Upper Mississippi River Valley.

Memphis, Tennessee

Dive into musical history at Graceland, Elvis Presley's legendary mansion and the second-most visited private home in America.

Natchez, Mississippi

Tour antebellum mansions perched on bluffs overlooking the Mississippi River where Southern history comes vividly alive.

Quad Cities

Paddle historic waterways and discover riverside museums showcasing America's heartland heritage and natural beauty.

Red Wing, Minnesota

Explore the Mississippi River's scenic bluffs and historic riverfront charm at this picturesque Minnesota gem nestled where water and nature converge.

Saint Louis, Missouri

Gaze up at the iconic Gateway Arch while strolling the revitalized riverfront that seamlessly blends St. Louis's rich history with modern urban charm.

Vicksburg, Mississippi

Explore Civil War battlefields and monuments at this historic riverside bluff that shaped American history.

Baton Rouge, Louisiana

Explore the magnificent Louisiana State Capitol, a 34-story Art Deco masterpiece offering panoramic river views and fascinating political history.

Cape Girardeau, Missouri

Discover the mighty Mississippi River's history at the Gateway Arch-inspired riverfront while exploring charming downtown shops and authentic regional cuisine.

Darrow, Louisiana

Paddle through misty bayou swamps teeming with alligators and ancient cypress trees draped in Spanish moss.

Paducah, Kentucky

Explore America's largest collection of outdoor murals transforming riverside walls into an open-air art gallery.

Saint Francisville, Louisiana

Explore stunning antebellum mansions nestled among Spanish moss-draped oaks along the serene Mississippi River bluffs.

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