Grand Heartland

📅 Friday, September 11, 2026 🏁 Saturday, September 26, 2026 🌙 14 Nights Saint Paul, Minnesota 🚢 American Heritage

Route Map

Day-by-Day Itinerary

Day 1
Saint Paul, Minnesota United States Explore the Minnesota History Center's impressive collections and stroll through vibrant neighborhoods along the scenic Mississippi River.
Arrive 2026-09-11 00:00:00
Day 2
Saint Paul, Minnesota United States Explore the Minnesota History Center's impressive collections and stroll through vibrant neighborhoods along the scenic Mississippi River.
Arrive 2026-09-11 00:00:00
Day 2
🌊 At Sea
Day 3
La Crosse, Wisconsin United States Cruise passengers can ride scenic riverboats through the majestic bluffs of the Upper Mississippi River Valley.
Arrive 2026-09-13 00:00:00
Day 4
Dubuque, Iowa United States Ride the historic riverboat casino and watch the Mississippi River roll by from scenic bluffs that rise 188 feet above the water.
Arrive 2026-09-14 00:00:00
Day 5
Davenport, Iowa United States Witness the mighty Mississippi River from the Figge Art Museum's stunning riverfront galleries in Iowa's cultural heartland.
Arrive 2026-09-15 00:00:00
Day 6
🌊 At Sea
Day 7
Hannibal, Missouri United States Explore the childhood home of Mark Twain and retrace the adventures of Tom Sawyer along the mighty Mississippi River.
Arrive 2026-09-17 00:00:00
Day 8
🌊 At Sea
Day 9
Saint Louis, Missouri United States Gaze up at the iconic Gateway Arch while strolling the revitalized riverfront that seamlessly blends St. Louis's rich history with modern urban charm.
Arrive 2026-09-19 00:00:00
Day 10
Memphis, Tennessee United States Dive into musical history at Graceland, Elvis Presley's legendary mansion and the second-most visited private home in America.
Arrive 2026-09-20 00:00:00
Day 11
Tunica, Mississippi United States Roll the dice at world-class casinos nestled along the Mississippi River in this thrilling gaming destination.
Arrive 2026-09-21 00:00:00
Day 12
🌊 At Sea
Day 13
Vicksburg, Mississippi United States Explore Civil War battlefields and monuments at this historic riverside bluff that shaped American history.
Arrive 2026-09-23 00:00:00
Day 14
Natchez, Mississippi United States Tour antebellum mansions perched on bluffs overlooking the Mississippi River where Southern history comes vividly alive.
Arrive 2026-09-24 00:00:00
Day 15
Baton Rouge, Louisiana United States Explore the magnificent Louisiana State Capitol, a 34-story Art Deco masterpiece offering panoramic river views and fascinating political history.
Arrive 2026-09-25 00:00:00

About This Cruise

Set sail on a spectacular journey along America’s most iconic waterway, where the unfolding narrative of the Mississippi River captures the essence of American history and tells the story of its landscapes. Enjoy a seamless blend of engaging shoreside excursions and unmatched onboard comfort. Each day is a new chapter, enriched by our dynamic guest speakers who share insights into the cultural and environmental backstories of the ports we visit. Travel through the Heartland where towns like Winona, Dubuque, and Davenport still hold the charm of bygone eras. Step back into the youthful days of Mark Twain with a memorable stop at his boyhood home in Hannibal. Experience the rhythm and blues of Memphis and the jazzy beats of New Orleans, cities celebrated for their monumental contributions to music. Wander through the stately homes of Natchez and tread across the hallowed grounds of Civil War sites in Vicksburg, each story passionately recounted by our expert guides. Back aboard, the evening sparkles with possibilities. Convene with fellow travelers over crafted cocktails, then dine in our elegant restaurant, all while river scenes gently shift past panoramic windows. Come aboard and weave your own story into the waves of America’s river lore. Just as it was back in Mark Twain’s day, every cruise on the Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary.
Mississippi River
From $8,754 per person 14 nights on American Heritage with American Cruise Lines
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