Grand Ohio River (Pittsburgh to St. Louis)

📅 Saturday, August 26, 2028 🏁 Saturday, September 9, 2028 🌙 14 Nights Pittsburgh, Pennsylvania 🚢 American Heritage
Balcony $7,333 per person
Visit American

Route Map

Day-by-Day Itinerary

Day 1
Pittsburgh, Pennsylvania United States Explore three iconic steel bridges and world-class museums along the scenic confluence of three rivers in America's revitalized Steel City.
Arrive 2028-08-26 00:00:00
Day 2
🌊 At Sea
Day 3
Marietta, Ohio United States Explore the historic Ohio River confluence where America's frontier began at the Campus Martius Museum and charming riverfront district.
Arrive 2028-08-28 00:00:00
Day 4
Maysville, Kentucky United States Trace American frontier history and bourbon heritage along the scenic Ohio River at this charming 19th-century riverport town.
Arrive 2028-08-29 00:00:00
Day 5
Cincinnati, Ohio United States Explore America's most intact Victorian riverfront and discover world-class museums in this historic Ohio River gateway city.
Arrive 2028-08-30 00:00:00
Day 6
Cincinnati, Ohio United States Explore America's most intact Victorian riverfront and discover world-class museums in this historic Ohio River gateway city.
Arrive 2028-08-31 00:00:00
Day 7
Louisville, Kentucky United States Cruise into the birthplace of bourbon and explore the legendary distilleries that shaped American whiskey history.
Arrive 2028-09-01 00:00:00
Day 8
Louisville, Kentucky United States Cruise into the birthplace of bourbon and explore the legendary distilleries that shaped American whiskey history.
Arrive 2028-09-02 00:00:00
Day 9
Henderson, Kentucky United States Explore the historic John James Audubon State Park and museum to discover wildlife artistry and Kentucky heritage along the scenic Ohio River.
Arrive 2028-09-03 00:00:00
Day 10
Evansville, Indiana United States Explore the impressive USS LST 325 warship and dive into American military history at this fully restored amphibious vessel.
Arrive 2028-09-04 00:00:00
Day 11
Paducah, Kentucky United States Explore America's largest collection of outdoor murals transforming riverside walls into an open-air art gallery.
Arrive 2028-09-05 00:00:00
Day 12
🌊 At Sea
Day 13
Cape Girardeau, Missouri United States Discover the mighty Mississippi River's history at the Gateway Arch-inspired riverfront while exploring charming downtown shops and authentic regional cuisine.
Arrive 2028-09-07 00:00:00
Day 14
Saint Louis, Missouri United States Gaze up at the iconic Gateway Arch while strolling the revitalized riverfront that seamlessly blends St. Louis's rich history with modern urban charm.
Arrive 2028-09-08 00:00:00
Day 15
Saint Louis, Missouri United States Gaze up at the iconic Gateway Arch while strolling the revitalized riverfront that seamlessly blends St. Louis's rich history with modern urban charm.
Arrive 2028-09-09 00:00:00

About This Cruise

Mississippi River
From $6,409 per person 14 nights on American Heritage with American Cruise Lines
Visit American