Point-to-Point

Naples to Santos Cruises

2 Cruises 1 Cruise Lines

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Cruise Line Cruises Ships From Duration Next Sailing
MSC Cruises 2 2 $1,394 19-21 nights Oct 28, 2027

All Cruises on This Route

Ports on This Route

Rio de Janeiro

Ride the cable car up to the iconic Christ the Redeemer statue for breathtaking views of Sugarloaf Mountain and the Atlantic coastline below.

Salvador de Bahia

Wander through cobblestone streets of Pelourinho's colonial mansions while soaking in Afro-Brazilian culture, music, and cuisine that pulses through this UNESCO-listed neighborhood.

Barcelona

Wander through whimsical architectural masterpieces and vibrant Gothic quarters where Gaudí's genius meets Mediterranean charm.

Civitavecchia

Wander through Rome's ancient Colosseum and Vatican treasures just an hour from the coast.

Genoa

Wander through the labyrinthine caruggi alleys where medieval palaces hide behind weathered facades and centuries of Genoese maritime history whisper from every corner.

Marseille

Explore the otherworldly Calanques National Park where towering limestone cliffs plunge into turquoise Mediterranean waters perfect for swimming and kayaking.

Santa Cruz de Tenerife

Wander through the vibrant plazas and museums of this historic port city nestled beneath the dramatic Anaga mountains.

Ilha Grande

Hike through lush Atlantic rainforest to pristine emerald beaches and hidden waterfalls cascading into crystalline turquoise waters.

Ilhabela

Dive into pristine Atlantic waters to snorkel shipwrecks and exotic marine life surrounding this lush island paradise.

Ilheus

Wander through the birthplace of Brazilian cacao in colonial architecture while sampling world-class chocolate in this charming coastal paradise.

Las Palmas de Gran Canaria

Wander through colorful colonial plazas and discover centuries of Canarian culture in this vibrant Atlantic port city.

Livorno

Wander through the Renaissance masterpiece of Pisa's Leaning Tower, just 25 minutes away by train from this charming Tuscan port city.

Maceió

Swim in crystalline lagoons and discover natural pools teeming with tropical fish in this Caribbean-like paradise along Brazil's northeastern coast.

Málaga

Wander through whitewashed villages clinging to dramatic cliffs while sipping crisp mountain wines in Spain's legendary Andalusian heartland.

Tarragona

Wander through remarkably preserved Roman ruins and amphitheaters overlooking the Mediterranean Sea.

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