Point-to-Point

Jacksonville, Florida to Saint Petersburg, Florida Cruises

16 Cruises 1 Cruise Lines

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Cruise Line Cruises Ships From Duration Next Sailing
American Cruise Lines 12 4 $9,810 14 nights Oct 21, 2026

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Amelia Island, Florida

Wander through centuries of pirate history and Spanish colonial charm in the picturesque streets of Fernandina Beach.

Key Biscayne, Florida

Dive into crystalline waters to explore the stunning coral reefs of the John Pennekamp Coral Reef State Park.

Key West, Florida

Sunset at Mallory Square transforms the waterfront into a bohemian celebration of street performers, artists, and spectacular tropical colors.

Marco Island, Florida

Paddle through mangrove tunnels and discover pristine white-sand beaches teeming with dolphins and tropical wildlife.

Port Canaveral, Florida

Blast off into space history at the Kennedy Space Center, where real rockets launch from nearby and astronaut encounters await.

Punta Gorda, Florida

Paddle through mangrove tunnels teeming with wildlife and spot dolphins in their natural habitat.

St. Augustine, Florida

Wander cobblestone streets lined with Spanish colonial architecture and discover America's oldest continuously occupied European settlement.

West Palm Beach, Florida

Stroll through world-class art museums and upscale boutiques in this glamorous waterfront town where tropical beauty meets sophisticated culture.

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