Upper Mississippi (St. Louis to St. Paul)

📅 Friday, July 23, 2027 🏁 Saturday, July 31, 2027 🌙 7 Nights Saint Louis, Missouri 🚢 American Serenade
Suite $7,925 per person
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Route Map

Day-by-Day Itinerary

Day 1
Saint Louis, Missouri United States Gaze up at the iconic Gateway Arch while strolling the revitalized riverfront that seamlessly blends St. Louis's rich history with modern urban charm.
Arrive 2027-07-23 00:00:00
Day 2
🌊 At Sea
Day 2
🌊 At Sea
Day 3
Hannibal, Missouri United States Explore the childhood home of Mark Twain and retrace the adventures of Tom Sawyer along the mighty Mississippi River.
Arrive 2027-07-25 00:00:00
Day 4
🌊 At Sea
Day 5
Muscatine, Iowa United States Discover the Mississippi River's pearl heritage and stroll charming riverfront trails lined with historic architecture and local art galleries.
Arrive 2027-07-27 00:00:00
Day 6
Dubuque, Iowa United States Ride the historic riverboat casino and watch the Mississippi River roll by from scenic bluffs that rise 188 feet above the water.
Arrive 2027-07-28 00:00:00
Day 7
Winona, Minnesota United States Explore the dramatic bluffs and rich riverboat heritage along the scenic Mississippi River in this charming historic town.
Arrive 2027-07-29 00:00:00
Day 8
Red Wing, Minnesota United States Explore the Mississippi River's scenic bluffs and historic riverfront charm at this picturesque Minnesota gem nestled where water and nature converge.
Arrive 2027-07-30 00:00:00

About This Cruise

Set off on an exhilarating journey on the Upper Mississippi River, where every moment resonates with the essence of hometown Americana and the breathtaking beauty that has captivated the imaginations of our nation's most revered writers, artists, and musicians. Feel the heartbeat of the great American spirit as you follow in the footsteps of literary legend Mark Twain, who found inspiration amidst the grandeur of the river and its cascading bluffs, immortalizing them in his iconic tales. Step into the pages of history as you travel to Hannibal, the very town that shaped Twain's storytelling, where the colorful characters of Huck Finn, Tom Sawyer, and Becky Thatcher spring to life. From the comfort of your own private balcony, take in the unspoiled landscapes, adorned with playful wildlife. Navigate through a labyrinth of enchanting islands and get up close to the ingenious engineering of dams and locks. As the river twists and turns, all your meals will reflect the landscape you pass. Every dish is thoughtfully curated, infused with the essence of local ingredients, ensuring each bite is a celebration of the rich culture that lines the shores of the upper Mississippi. Join our river cruise from St. Louis to St. Paul and let the energy of this remarkable journey ignite your spirit and leave you with memories to cherish for a lifetime.
Mississippi River
From $4,472 per person 7 nights on American Serenade with American Cruise Lines
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